What is AHK-Cu?
Short peptide AHK-Cu is chemically bonded to a copper ion. In AHK, the alanine and histidine residues of the alanine-histidine-lysine peptide are connected by a copper atom. Three nitrogen atoms in the tripeptide are covalently bonded to the copper atom. In addition to its extensive study as a skin conditioner, AHK-Cu has lately attracted attention as a possible cure for hair loss based on encouraging laboratory tests. Buy AHK-Cu topical peptide if you are a researcher.
Copper peptides: what are they?
Copper peptides are an effective antioxidant that has many positive effects on hair and skin. Antioxidants have been more popular in the cosmetics industry over the last decade. Learning more about them is essential for anybody who wants to maintain healthy hair, scalp, and skin. Because of the many beneficial elements they contain, copper peptides are also pertinent to the issue of hair loss prevention.
Compounds of Copper and Dihydrotestosterone (DHT)
Androgenic alopecia, often known as pattern hair loss, is the most prevalent form of baldness in adult males. In most cases, elevated levels of the hormone dihydrotestosterone are to blame for androgenic alopecia (DHT).
The hormone dihydrotestosterone (DHT) is critical to developing the adult body. On the other hand, DHT levels might increase with age, stunting the hair’s growth.
As a result of DHT’s decreasing impact on the follicles, the hair may grow more slowly, unevenly, and in thinner strands. Localized balding might occur if the DHT levels are too high.
The most noticeable symptoms of the androgenic alopecia in males are a thinning hairline and the development of a bald area on top of the head. For females, androgenic alopecia may cause comparable hair loss but more typically affects the division, or portion, in a female’s hair.
Copper peptides naturally counteract the follicle-shrinking, growth-slowing effects of DHT, which is one of the hair’s main advantages of copper peptides. Because copper peptides are potent natural DHT-blockers, they should be a part of any hair loss prevention strategy.
Use in Research
The significant interest in AHK-Cu is in how it affects fibroblasts, the cells responsible for developing and maintaining the extracellular matrix (the stuff between cells). Vascular endothelial growth factor (VEGF) is one of the chemicals secreted by fibroblasts that encourages the development of new blood vessels. Using animal and laboratory models, the cosmeceutical industry has conducted significant research into the benefits of AHK-Cu on skin health, collagen formation, and hair growth.
Studies on AHK-Cu and the Fight Against Wrinkles
Sunscreens and skin lotions often include copper or copper peptides as an ingredient. Animal studies have shown that AHK-Cu significantly increases collagen production. The effects of collagen on the skin are many and significant. The first benefit is that it makes the skin more rigid and firm. Furthermore, collagen has a natural affinity for water. Wrinkles and fine lines may be diminished by the hydrating effects of water on the skin’s cells and extracellular matrix. It has been shown in animal models that AHK-Cu may effectively lessen the appearance of wrinkles.
Investigating the Role of AHK-Cu in Hair Loss
The AHK-Cu compound has a dual impact on balding. To begin with, it aids in developing new blood vessels by increasing VEGF production. Hair follicles can’t thrive without the nutrients carried to them by the blood vessels. Animal studies reveal that AHK-Cu not only increases blood flow to already established hair follicles but also stimulates the development of new blood vessels, resulting in the formation of new hair follicles.
The second mechanism- AHK-Cu, contributes to hair loss is inhibiting transforming growth factor-beta 1. Dihydrotestosterone (DHT) is a powerful hormone in age-related hair loss in males and females, often known as male pattern baldness. DHT relies on transforming growth factor Î21 (TGF21) to exert many of its actions. AHK-Cu may mitigate the effects of DHT and shield hair follicles from damaging stress by lowering levels of transforming growth factor Î21.
In this case, a valuable article from the newspaper Etemad (No. 2305, November 2011) was translated by Ms. Nastaran Saabi and will be shown as soon as possible.